What is Cannabigerol (CBG)?

Cannabis’ minor constituent with major benefits 

While THC and CBD are widely studied cannabinoids, Cannabigerol is a lesser-known cannabinoid that is growing in popularity. Just like Cannabinol (CBN), CBG is not a psychoactive cannabinoid. Meaning, people who use CBG will not experience intoxicating effects like changes to their visual perception, time perception, and it will not impact users' short-term memory. 

Glossary 

To understand how CBG and other cannabinoids interact with the body, the following definitions are provided for the types of molecules, systems, and parts referenced. 

Cannabinoid - A specific classification of compounds, usually produced naturally via plants and animals, but can be synthetically manufactured. 

Phytocannabinoid  - Cannabinoids that are formed inside a plant. 

Endocannabinoid - Cannabinoids that are formed inside an animal's body. 

Endocannabinoid system, A biological system of neurotransmitters that bind to cannabinoid receptors and receptor proteins. Also known as “ESC.”

Cannabinoid Receptor 1, or CB1 receptor, is one of the two pivotal components of the ECS, they play an important role in regulating motor control, the capacity to feel pain, emotional regulation, and reward processing. 

Cannabinoid Receptor 2, or CB2 receptor, modulates the functions of immune cells and limits how much pro-inflammatory stimuli is released. 

Cannabigerol, also known as: CBG

Cannabigerol, also known as CBG, is a unique molecular mechanism with a therapeutic profile full of potential. While its activity within the Endocannabinoid System (ESC) and characteristics are similar to those of other cannabinoids, for example, producing effects by binding to CB1 and CB2 receptors. 

Researchers are investigating CBG’s therapeutic applications for treating inflammation, combating bacterial infections, managing hypotension, aiding in cancer treatment, alleviating pain, and addressing metabolic syndrome. 

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Source Citations 

Jastrząb, A., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2022). The Origin and Biomedical Relevance of Cannabigerol. International Journal of Molecular Sciences, 23(14), 7929. https://doi.org/10.3390/ijms23147929 

Li, S., Li, W., Malhi, N. K., Huang, J., Li, Q., Zhou, Z., Wang, R., Peng, J., Yin, T., & Wang, H. (2024). Cannabigerol (CBG): A Comprehensive Review of Its Molecular Mechanisms and Therapeutic Potential. Molecules, 29(22), 5471. https://doi.org/10.3390/molecules29225471